MESSENGER-RNA ATTACHMENT TO ACTIVE RIBOSOMES
نویسندگان
چکیده
منابع مشابه
Messenger-RNA attachment to active ribosomes.
16 In a current experiment, we have found that a protein fraction isolated from the 105,000 X g supernatant can catalyze a similar RNA synthesis in the presence of four nucleoside triphosphates and the E. coli DNA prepared by the method of Marmur (J. Mol. Biol., 3, 208, 1961). In this system also, the addition of salmine enhances the initial rate of the synthesis and prevents the degradation of...
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The Biochemical Society's Forty-Seventh Symposium, held in London in December 1981, assembled some of the leading workers in this area of biochemistry. The subjects for discussion were chosen for their timeliness and distinctiveness, and included accounts of ribosome and messenger RNA structure and function, initiation factors, caps and ribonucleoproteins, as well as consideration of the proces...
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In a recent paper by Valleriani et al. [Phys. Rev. E 83, 042903 (2011)], a simple model for the translation of messenger RNA (mRNA) is presented. Using this model, the protein translational ratio r, defined as the ratio of protein translation rate ω(tl) from mRNA to protein degradation rate ω(p), is obtained. The key point in obtaining the translational ratio r is to get the protein translation...
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The gene for subunit II of cytochrome oxidase (CoII) from bovine mitochondria has been cloned behind a T7 promoter and the corresponding mRNA synthesized in vitro. The RNA transcribed from this vector has a single nucleotide 5' to the start AUG and, thus, corresponds closely to the native mRNA. It binds to the small 28 S ribosomal subunit of bovine mitochondria but not to the large (39 S) subun...
متن کاملLength-dependent translation of messenger RNA by ribosomes.
A simple measure for the efficiency of protein synthesis by ribosomes is provided by the steady state amount of protein per messenger RNA (mRNA), the so-called translational ratio, which is proportional to the translation rate. Taking the degradation of mRNA into account, we show theoretically that both the translation rate and the translational ratio decrease with increasing mRNA length, in ag...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1962
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.48.3.430